Sep 8 2016

Neurons floating upside down

September 8, 2016

4:00 PM - 5:00 PM

Location

4289 SEL, 840 West Taylor St.

Abstract

The progress of modern medicine extends human lifespan. With this progress, however, come new challenges. The still incurable neurological disorders associated with aging such as Alzheimer’s or Parkinson’s diseases are affecting progressively larger percentage of the population. The need to find and test new drugs to treat these diseases becomes more and more pressing. Prior to testing these new drugs in clinical trials or even in animals, the drugs will be tested in vitro on cultured cells. To this end, new cell culture models need to be developed and the tools used for cell culturing need to be improved. The seminar will discuss novel tools and cell culture models developed in Dr. Kiedrowski’s laboratory. The discussion will include cell cultures obtained from cryopreserved preparations, hybrid co-cultures of neurons and fluorescently-tagged astrocytes, sandwich co-cultures of neurons and astrocytes, and novel chambers to grow and image cultured cells. An application of these cell culture models to study intracellular ion (Ca2+, Zn2+, and H+) homeostasis will also be presented.

 For more information, check out Dr. Kiedrowski's webpage.

Hybrid neuro-glial co-culture

Lech[1]

Contact

N/A
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Date posted

Aug 13, 2018

Date updated

Aug 13, 2018