Spring Symposium in Neuroscience: Gut Instinct: The influence of the gut on brain and behavior (Please note location and time)
April 20, 2017
10:30 AM - 1:30 PM
Room 605, Student Center East, 750 South Halsted
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The symposium will feature two fantastic speakers (Jane Foster, McMaster University and John Cryan, University College Cork) as well as LIN graduate students presenting data blitzes about their research.
The schedule for the symposium is:
1:20 Data blitz by LIN graduate students
Here is more detailed information about the talks.
Dr. Jane Foster, Associate Professor, Department of Psychiatry & Behavioural Neurosciences, McMaster University: "Mood and microbes - an overview of how microbes influence brain and behavior"
Dr. John Cryan, Professor and Chair, Anatomy and Neuroscience, University College Cork, Ireland: "A Gut Feeling About the Brain: The microbiota as a key regulator of neurodevelopment and behavior"
Abstract: The brain-gut-microbiota axis is emerging as a research area of increasing interest for those investigating the biological and physiological basis of neurodevelopmental, age-related and neurodegenerative disorders. The routes of communication between the gut and brain include the vagus nerve, the immune system, tryptophan metabolism, via the enteric nervous system or by way of microbial metabolites such as short chain fatty acids. Studies in animal models have shown that the development of an appropriate stress response is dependent on the microbiota. Developmentally, a variety of factors can impact the microbiota in early life including mode of birth delivery, antibiotic exposure, mode of nutritional provision, infection, stress as well as host genetics. At the other extreme of life, individuals who age with considerable ill health tend to show narrowing in microbial diversity. Stress can significantly impact the microbiota-gut-brain axis at all stages across the lifespan Recently, the gut microbiota has been implicated in a variety of conditions including autism, schizophrenia and Parkinson’s disease. Moreover, fundamental brain processes from adult hippocampal neurogenesis to myelination to microglia activation have been shown to be regulated by the microbiome. Further studies will focus on understanding the mechanisms underlying such brain effects and developing nutritional and microbial-based intervention strategies. publish.ucc.ie/researchprofiles/C003/jcryan Twitter: @jfcryan
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